Currently, there is a high increase in the development of animal husbandry, including pig farming where modem veterinary technologies aimed, primarily, at performing clear prophylactic measures for the prevention of postpartum diseases, the stimulating the reproductive system and producing healthy offspring are widely introduced. For this purpose in daily practice various new tools, including biologically active substances having a positive impact on neuroendocrine relationships, stimulating the immunogenesis and metabolic processes in the animal organism are introduced. However, given the production data of the farms, the issue remains relevant. The purpose of our research was to study the properties of hormone therapy with gamavit and gipofezin La Wayx on the body of sows after farrowing. These studies were carried out in the conditions of pig farm JSC "Trinity" of Gubkin district of the Belgorod region in winter-spring period in the sows on the sixth delivery having the mass of 180 kg. Four groups of sows (n=40) were chosen immediately after birth. The first group of sows on the first day after farrowing was injected intramuscularly four times gamavit in the dose of 10 ml/bird/day at 1st, 3rd, 5th, 7th day and hypophysis, only in the beginning of the course (on 1st day) single dose of 1 ml/bird/day. In the second group drugs were administered in a similar course, starting from 15th day after birth - on the 15th, 17th, 19th and 22nd days. In the third group of animals gamavit and hypophisis were administered in the same doses, but starting from 20th day afterbirth - on the 20th, 22nd, 24th and 26th day. The fourth group of sows included the control and intact animals. Five sows in each group were examined taking blood from ear vein four times during the study period (on 1st, 15th, 21st, 26th day) to conduct laboratory tests of blood to determine the amounts of estradiol-176, progesterone, FSH, cortisol, thyroxine. After the research it was noted that there was a greater increase to 26 days after delivery, levels of estradiol-17β and more FSH and reduced levels of progesterone and cortisol in comparison with the other three groups, as well as increasing the level of thyroxine in the 3rd and 4th groups. The use of gamavit intramuscularly after childbirth in dose 10 ml/head/day at 20th, 22nd, 24th, 26th day and gipofezin La wax on the 20 th day, a single dose of 1 ml contributed to a better fertilization 95,0% of the sows within the shortest of period 6 days after weaning, average of 14 piglets per animal with the least amount of 2.5% of animals with MMA. Thus, the use of Biocorrector gamavit and gipofezin La Wayx allows you to stimulate the neuroendocrine interactions in the body, improve reproductive function and prevent disease postpartum.