The results of the researches conducted within obligatory monitoring of safety medicine for veteri-nary application "Tanis" are presented in the study. The preparation represents thermal cardboard plates of 20 × 50 × 1 mm in size impregnated with oxidizer and active ingredient fluvalinate. For the treatment of bees the plate was set afire and intro-duced into the bottom of hive entrance and it was closed for 20 minutes. Acaricide is registered in the Russian Federation and entered in the register of medicines for veterinary application. The research objective was confirmation of therapeutic efficiency of «Tanis» acaricide at varroatosis and its safety for bees and products of beekeeping. The researches were conducted on apiaries of Tyumen Region and in the Laboratory of diseases of bees of All-Russian Research Institute of Veterinary Entomology and Arachnology according to "Methodical recommen-dations on studying of receptions and means of fight against varroa mite. In the course of perfor- mance of work acaricide efficiency of preparation at varroatosis was defined, its influence on the devel-opment of bee families was investigated, the defini-tion of the remains of active ingredient in beekeep-ing products was carried out. It was established that 4 days of processing of bee families, three times with an interval, with the brood the number of varroa mite was reduced 92.0 %, the efficiency of double processing of families without brood by "Ta-nis" made 98.04 %. Negative influence of "Tanis" was on physiological condition of bee families; the death of open, printing brood and uterus were not revealed. In all studied tests specimens of honey and wax the remains of fluvalinat were not re-vealed.